This tool provides a lot of facility-like models with key-value binding and custom events, API of enumerable functions, views, and other useful rich APIs that help to create a modern application.
This library is good for developing complex and cross browser web pages in a simple way.
Sencha Ext JS is the industry's most powerful desktop application development platform with unparalleled cross-browser compatibility, advanced MVC architecture, plugin-free charting, and modern UI widgets.
Serenade.js is a client-side framework that also creates rich client-side applications.
Feathers is one of the most popular light-weight web application framework for nodejs. I also creates RESTful web services and real-time applications.